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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: KCY_HUMAN




USC-OGP 2-DE database:  KCY_HUMAN

KCY_HUMAN


General information about the entry
View entry in simple text format
Entry nameKCY_HUMAN
Primary accession numberP30085
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=UMP-CMP kinase {ECO:0000255|HAMAP-Rule:MF_03172}; EC=2.7.4.14 {ECO:0000255|HAMAP-Rule:MF_03172}; AltName: Full=Deoxycytidylate kinase {ECO:0000255|HAMAP-Rule:MF_03172}; Short=CK {ECO:0000255|HAMAP-Rule:MF_03172}; Short=dCMP kinase {ECO:0000255|HAMAP-Rule:MF_03172}; AltName: Full=Nucleoside-diphosphate kinase {ECO:0000255|HAMAP-Rule:MF_03172}; EC=2.7.4.6 {ECO:0000255|HAMAP-Rule:MF_03172}; AltName: Full=Uridine monophosphate/cytidine monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03172}; Short=UMP/CMP kinase {ECO:0000255|HAMAP-Rule:MF_03172}; Short=UMP/CMPK {ECO:0000255|HAMAP-Rule:MF_03172};.
Gene nameName=CMPK1 {ECO:0000255|HAMAP-Rule:MF_03172}
Synonyms=CMK, CMPK {ECO:0000255|HAMAP-Rule:MF_03172}, UCK, UMK, UMPK
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_4-7 {PLATELET 4-7}
Homo sapiens (Human)
PLATELET_4-7
  map experimental info 		 
PLATELET_4-7

MAP LOCATIONS:
pI=5.37; Mw=21509



PLATELET_5-6 {PLATELET 5-6}
Homo sapiens (Human)
PLATELET_5-6
  map experimental info 		 
PLATELET_5-6

MAP LOCATIONS:
pI=5.33; Mw=18985



UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info 		 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=5.70; Mw=23333
pI=5.50; Mw=22988

Cross-references
UniProtKB/Swiss-ProtP30085; KCY_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameKCY_HUMAN
Primary accession numberP30085
Secondary accession number(s) B4DPU7 E9PGI8 Q53GB7 Q5SVZ0 Q96C07 Q9UBQ8 Q9UIA2
Sequence was last modified on December 1, 2000 (version 3)
Annotations were last modified on March 15, 2017 (version 178)
Name and origin of the protein
DescriptionRecName: Full=UMP-CMP kinase {ECO:0000255|HAMAP-Rule:MF_03172}; EC=2.7.4.14 {ECO:0000255|HAMAP-Rule:MF_03172}; AltName: Full=Deoxycytidylate kinase {ECO:0000255|HAMAP-Rule:MF_03172}; Short=CK {ECO:0000255|HAMAP-Rule:MF_03172}; Short=dCMP kinase {ECO:0000255|HAMAP-Rule:MF_03172}; AltName: Full=Nucleoside-diphosphate kinase {ECO:0000255|HAMAP-Rule:MF_03172}; EC=2.7.4.6 {ECO:0000255|HAMAP-Rule:MF_03172}; AltName: Full=Uridine monophosphate/cytidine monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03172}; Short=UMP/CMP kinase {ECO:0000255|HAMAP-Rule:MF_03172}; Short=UMP/CMPK {ECO:0000255|HAMAP-Rule:MF_03172};
Gene nameName=CMPK1 {ECO:0000255|HAMAP-Rule:MF_03172}
Synonyms=CMK, CMPK {ECO:0000255|HAMAP-Rule:MF_03172}, UCK, UMK, UMPK
Encoded onName=CMPK1 {ECO:0000255|HAMAP-Rule:MF_03172}; Synonyms=CMK, CMPK {ECO:0000255|HAMAP-Rule:MF_03172}, UCK, UMK, UMPK
Keywords3D-structure; Acetylation; Alternative splicing; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Pyrimidine biosynthesis; Reference proteome; Transferase.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAF070416; AAF17709.1; ALT_INIT; mRNA
EMBLAF259961; AAG22609.1; -; mRNA
EMBLAF110643; AAD48583.1; -; mRNA
EMBLAF087865; AAP97174.1; -; mRNA
EMBLAF112216; AAF17204.1; -; mRNA
EMBLAK223014; BAD96734.1; ALT_INIT; mRNA
EMBLAK298502; BAG60709.1; ALT_INIT; mRNA
EMBLAL513322; CAI13471.1; ALT_SEQ; Genomic_DNA
EMBLAL607122; CAI13471.1; JOINED; Genomic_DNA
EMBLAL607122; CAI14972.1; ALT_SEQ; Genomic_DNA
EMBLAL513322; CAI14972.1; JOINED; Genomic_DNA
EMBLBC014961; AAH14961.1; ALT_INIT; mRNA
PIRB45482; B45482; .
RefSeqNP_001129612.1; NM_001136140.1; .
RefSeqNP_057392.1; NM_016308.2; .
UniGeneHs.731647; -; .
UniGeneHs.745001; -; .
PDB1TEV; X-ray; 2.10 A; A=1-196
PDBsum1TEV; -; .
ProteinModelPortalP30085; -; .
SMRP30085; -; .
BioGrid119700; 10; .
IntActP30085; 1; .
MINTMINT-5000978; -; .
STRING9606.ENSP00000360939; -; .
ChEMBLCHEMBL5681; -; .
DrugBankDB03403; Cytidine-5'-Monophosphate; .
DrugBankDB00441; Gemcitabine; .
DrugBankDB00709; Lamivudine; .
DrugBankDB03664; P1-(Adenosine-5'-P5-(Uridine-5')Pentaphosphate; .
DrugBankDB04444; Tetrafluoroaluminate Ion; .
DrugBankDB03435; Uridine-5'-Diphosphate; .
iPTMnetP30085; -; .
PhosphoSitePlusP30085; -; .
SwissPalmP30085; -; .
DMDM12644008; -; .
OGPP30085; -; .
SWISS-2DPAGEP30085; -; .
EPDP30085; -; .
MaxQBP30085; -; .
PaxDbP30085; -; .
PeptideAtlasP30085; -; .
PRIDEP30085; -; .
TopDownProteomicsP30085-1; -. [P30085-1]; .
DNASU51727; -; .
EnsemblENST00000371873; ENSP00000360939; ENSG00000162368; .
EnsemblENST00000450808; ENSP00000398192; ENSG00000162368; .
GeneID51727; -; .
KEGGhsa:51727; -; .
UCSCuc001cri.3; human. [P30085-1]; .
CTD51727; -; .
DisGeNET51727; -; .
GeneCardsCMPK1; -; .
HGNCHGNC:18170; CMPK1; .
HPAHPA053730; -; .
HPAHPA058604; -; .
MIM191710; gene; .
neXtProtNX_P30085; -; .
PharmGKBPA162382539; -; .
eggNOGKOG3079; Eukaryota; .
eggNOGCOG0563; LUCA; .
HOGENOMHOG000238771; -; .
HOVERGENHBG108060; -; .
InParanoidP30085; -; .
KOK13800; -; .
OrthoDBEOG091G0OQ7; -; .
PhylomeDBP30085; -; .
TreeFamTF354283; -; .
BioCycMetaCyc:HS08663-MONOMER; -; .
BRENDA2.7.4.14; 2681; .
ReactomeR-HSA-499943; Synthesis and interconversion of nucleotide di- and triphosphates; .
SABIO-RKP30085; -; .
ChiTaRSCMPK1; human; .
EvolutionaryTraceP30085; -; .
GeneWikiCMPK; -; .
GenomeRNAi51727; -; .
PROPR:P30085; -; .
ProteomesUP000005640; Chromosome 1; .
BgeeENSG00000162368; -; .
CleanExHS_CMPK1; -; .
ExpressionAtlasP30085; baseline and differential; .
GenevisibleP30085; HS; .
GOGO:0005737; C:cytoplasm; TAS:ProtInc; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0005730; C:nucleolus; IDA:HPA; .
GOGO:0005634; C:nucleus; IDA:HPA; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0004127; F:cytidylate kinase activity; IEA:UniProtKB-EC; .
GOGO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB; .
GOGO:0050145; F:nucleoside phosphate kinase activity; EXP:Reactome; .
GOGO:0004849; F:uridine kinase activity; TAS:ProtInc; .
GOGO:0009041; F:uridylate kinase activity; IEA:InterPro; .
GOGO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:InterPro; .
GOGO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome; .
GOGO:0006165; P:nucleoside diphosphate phosphorylation; IDA:UniProtKB; .
GOGO:0009142; P:nucleoside triphosphate biosynthetic process; IDA:UniProtKB; .
GOGO:0009220; P:pyrimidine ribonucleotide biosynthetic process; TAS:ProtInc; .
CDDcd01428; ADK; 1; .
Gene3D3.40.50.300; -; 1; .
HAMAPMF_00235; Adenylate_kinase_Adk; 1; .
HAMAPMF_03172; Adenylate_kinase_UMP_CMP_kin; 1; .
InterProIPR000850; Adenylat/UMP-CMP_kin; .
InterProIPR033690; Adenylat_kinase_CS; .
InterProIPR027417; P-loop_NTPase; .
InterProIPR006266; UMP_CMP_kinase; .
PANTHERPTHR23359; PTHR23359; 1; .
PRINTSPR00094; ADENYLTKNASE; .
SUPFAMSSF52540; SSF52540; 1; .
TIGRFAMsTIGR01359; UMP_CMP_kin_fam; 1; .
PROSITEPS00113; ADENYLATE_KINASE; 1; .


USC-OGP 2-DE database image

Gateways to other related servers

Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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